Montgomery College 2019-2020 Catalog 
    
    Mar 28, 2024  
Montgomery College 2019-2020 Catalog [ARCHIVED CATALOG]

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BIOT 250 - Principles of Biomanufacturing


(G only)

An introduction to the process of producing a biological product using a cell line. The course will be organized as a production campaign in a simulated cGMP environment. Students will complete a batch record as they produce a biological product. Emphasis will be on upstream and downstream processes. Hands-on laboratory work will involve the preparation and qualification of growth media and chromatography buffers, the use of bioreactors and FPLC protein purification systems. The role of QA/QC will be discussed. PREREQUISITE(S): BIOT 120 ; BIOT 200  or consent of department. Three hours lecture, three hours laboratory each week. Formerly BT 235.

4 semester hours

Course Outcomes:
Upon course completion, a student will be able to:

  • Define the elements of cGMP.
  • Explain upstream processing.
  • Explain downstream processing.
  • Assemble and run growth vessels for insect or mammalian cells.
  • Assemble and run protein purification equipment.


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