BIOT 260 - Introduction to the Principles of Cell and Gene Therapy

(G only)

Introduction to the basic concepts of cell and gene therapies. Viral and non-viral vectors will be described in detail with respect to vector characteristics and selection, production, and purification. Cell therapies will focus on cell collection, engineering, and scale out for cells commonly used in therapies (CAR-T, MSC, iPSC). The importance of cGMP and critical quality attributes for each will be included. PREREQUISITE(S): BIOT 120, BIOT 200, and BIOT 240. Three hours lecture each week.

3 semester hours

Course Outcomes:
Upon completion of this course, a student will be able to:

Define Cell, Gene Therapy, and related terms.
Describe different vectors used in cell and gene therapies.
Describe the production process, including purification of vectors and cells.
Describe the critical regulatory requirements for cell and gene therapies.
List Cell and Gene Therapy companies in Maryland.
Describe one or more specific cell or gene therapy approved or in clinical trials.

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